WebbAbstract. Dry eye disease (DED) is a chronic ocular surface disorder, associated with inflammation, which can cause severe morbidity, visual compromise, and loss of quality of life, affecting up to 5–50% of the world population. In DED, ocular surface damage and tear film instability due to abnormal tear secretion lead to ocular surface pain ... Webb10 apr. 2024 · The COVID-19 pandemic caused by SARS-CoV-2 is associated with a lower fatality rate than its SARS and MERS counterparts. However, the rapid evolution of SARS-CoV-2 has given rise to multiple variants with varying pathogenicity and transmissibility, such as the Delta and Omicron variants. Individuals with advanced age or underlying …
Involvement of the Mitochondrial Benzodiazepine Receptor in …
WebbTherapeutic considerations for elderly hypertensives. Therapeutic considerations for elderly hypertensives Clin Ther. 1982;5 Spec No:25-38. Authors R J Anderson, G Reed, L … WebbImmunogenic cell death in cancer: concept and therapeutic implications Lorenzo Galluzzi, Oliver Kepp, Erik Hett, Guido Kroemer, Francesco M. Marincola; Affiliations ... Here, we critically discuss key conceptual and mechanistic aspects of ICD and its implications for cancer (immuno)therapy. Keywords. Antigenicity mephisto explorer
Design of dosage forms Clinical Gate
WebbExtensive research has identified a vast range of deleterious signals that are generated and integrated at the mitochondrial level resulting in impairment of major mitochondrial functions such as calcium homeostasis, free radicals generation and detoxification, energy production and neurosteroidogenesis. Webb11 apr. 2024 · Mucosal barriers are essential for protecting the organism from environmental antigens. However, when the immune response at these sites is dysregulated, it can lead to the development of allergic diseases. The ocular, respiratory, gastrointestinal, and genitourinary tracts are particularly susceptible due to their … WebbAn evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia Marilisa Bove, Arrigo Francesco Giuseppe Cicero, Maddalena Veronesi, Claudio Borghi Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy Abstract: Several studies suggest that chronic hyperuricemia, the … mephisto exclusive batteriefach