Phospho eif4b

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August undefined, 2024

WebAnti-eIF4B (phospho S422) antibody See all eIF4B primary antibodies Description Rabbit polyclonal to eIF4B (phospho S422) Host species Rabbit Tested applications Suitable for: … WebJan 25, 2024 · We hypothesised that the effect of SLC25A11 knockdown on inhibiting protein translation was mediated by the inactivation of translational elongation factors such as eIF4B through the depletion of the ATP supply, which resulted in a critical reduction of p-eIF4B dependent synthesis of proteins including c-Myc in cancer cells (Fig. 4 b).

Phosphorylation of eukaryotic initiation factor-2α (eIF2α ... - Nature

WebProduct Details Target Information The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. WebJan 25, 2024 · We hypothesised that the effect of SLC25A11 knockdown on inhibiting protein translation was mediated by the inactivation of translational elongation factors … great clips tecumseh hours

SignalSilence® eIF4B siRNA Cell Signaling Technology

WebAll lanes : Anti-eIF4B (phospho S504) antibody [EP2261Y] (ab75823) at 1/50000 dilution Lane 1 : 293T cell lysate, untreated Lane 2 : 293T cell lysate, treated with AP Lysates/proteins at 10 µg per lane. Secondary All lanes : goat anti-rabbit HRP at 1/2000 dilution Predicted band size: 69 kDa Observed band size: 69 kDa WebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins … WebPhospho-eIF4B (Ser406) Antibody detects endogenous levels of eIF4B protein only when phosphorylated at Ser406. Species Reactivity: Human, Mouse. Species predicted to react … great clips tecumseh

Muscarinic acetylcholine receptors mediate eIF4B phosphorylation …

Anti-eIF4B (phospho S422) antibody (ab59300) Abcam

WebNov 18, 2016 · The activity of eIF4B is modulated by phosphorylation, which is mediated by two major signaling pathways, the MEK1/2-ERK1/2-RSK pathway and the PI3K-Akt-mTORC1-S6K pathway [8], [9], [11], [12]. Overexpression or depletion of eIF4B affects cell survival and proliferation [13], [14]. WebJan 5, 2024 · The translation initiation factor eIF4A is a member of the “DEAD box” family of helicases that catalyze the ATP-dependent unwinding of RNA duplexes and facilitates 43S ribosome complex scanning through highly structured regions of the 5′-untranslated region (UTR) and recognition of the AUG initiation codon. great clips taylorvilleWebInvitrogen Anti-Phospho-EIF4B (Ser504) Polyclonal, Catalog # PA5-114571. Tested in Western Blot (WB), Immunocytochemistry (ICC/IF) and Immunohistochemistry (PFA fixed) … great clips tecumseh mi sign in

"WebRecombinant Anti-eIF4B (phospho S406) antibody [EPR7683] - BSA and Azide free (ab248698) Datasheet Certificate of Compliance Submit a review Submit a question Product price, shipping and contact information Currently … " - Phospho eif4b

Phospho eif4b

Loss of SLC25A11 causes suppression of NSCLC and melanoma …

WebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using phospho-EIF4B-S422 antibody (AP0278). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. Web酶联生物为您提供大鼠热休克蛋白β6(hspβ6)检测试剂盒的参数及2024年最新报价，厂家专业的大鼠热休克蛋白β6(hspβ6)检测试剂盒售后服务团队，是您值得信赖的合作伙伴

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WebSep 5, 2024 · eIF4B phosphorylation patterns in hippocampal neurons and cortical astrocytes. ( A) Western blot analysis of total cell extracts from neurons or astrocytes … WebAug 17, 2014 · Phospho-proteomics identified the mTOR pathway to be of interest in EGFR inhibitor resistance. In our studies, combining gefitinib and temsirolimus decreased cell growth and survival in a synergistic manner. Our data identified eIF4B, as a potentially key fragile point in EGFR and mTOR inhibitor synergy.

WebEIF4B Antibody (phospho-Ser422) LS-C826726 Antibody: EIF4B Rabbit anti-Human Polyclonal (pSer422) Antibody . Reactivity: Mouse, Rat, Human . Applications: ELISA, IF, IHC, WB . Format: Unconjugated . Price: 1 mg/$357. Select. EIF4B Antibody LS-C334046 Antibody: EIF4B Rabbit anti-Human Polyclonal Antibody ... WebHuman Phospho-eIF4B (S422) Antibody Summary Species Reactivity Human Specificity Detects human eIF4B when phosphorylated at S422 Source Monoclonal Rat IgG 2A Clone # 866049 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Phosphopeptide containing the human eIF4B S422 site Formulation

WebThe eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. WebAnti-eIF4B (phospho S422) antibody See all eIF4B primary antibodies Description Rabbit polyclonal to eIF4B (phospho S422) Host species Rabbit Tested applications Suitable for: IHC-P, WB, ICC/IF more details Species reactivity Reacts with: Mouse, Human Immunogen Synthetic peptide corresponding to Human eIF4B aa 350-450 (phospho S422). T-G-SP-E-S

WebRecombinant Recombinant Anti-eIF4B (phospho S406) antibody [EPR7683] (ab134138) Datasheet SDS Submit a review Submit a question References (2) Key features and details Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal [EPR7683] to eIF4B (phospho S406) Suitable for: …

WebPhospho-EIF4B-S422 Rabbit pAb (AP0278) Datasheet SDS Tested applications: WB IHC Reactivity: Human, Mouse Western blot analysis of extracts from HeLa cells using … great clips taylor txWebEIF4B is one of the mammalian eukaryotic initiation factors (eIF) that are required for the ATP-dependent binding of mRNA to the 40 S ribosomal subunit, and the other eIF proteins are EIF4A, EIF4F. eIF4B is involved in translation of numerous proliferative or anti-apoptotic mRNAs with highly structured 5'UTR and subsequently affect cell growth … great clips teel friscoWebWestern blot analysis of extracts from HeLa cells, untransfected or transfected with SignalSilence ® eIF4B siRNA #6416, using Phospho-eIF4B (Ser422) Antibody (upper) or eIF4B Antibody #3592 (lower). 48 hours following transfection, cells were treated with Rapamycin (50 nM) and U0126 (10 uM) as indicated. great clips tega cay online check-inWebAug 4, 2024 · Phosphorylated eIF4B levels are normalized against total eIF4B, then for loading (Tubulin) and shown as fold change over control (untreated neurons). Data are … great clips tehama ridge fort worth txWeb上海谷研实业有限公司主要从事免疫学、分子生物学和常规生化试剂的销售,主营产品:生化试剂、试剂盒、elisa试剂盒、抗体、重组蛋白、生化检测试剂盒、分光光度法检测试剂盒、荧光定量pcr检测试剂盒、细胞株、原代细胞、细胞培养基、标准溶液产品。 great clips telford paWebJun 8, 2024 · The phosphorylation of eIF2α occurs on serine 51 in response to the activation of one out of four eIF2α kinases 4, 5, 6. EIF2AK1, commonly known as heme-regulated inhibitor (HRI), is activated by... great clips tejas centerWebPhospho-eIF4E (Ser209) Antibody detects endogenous levels of eIF4E only when phosphorylated at serine 209. Species Reactivity: Human, Mouse, Rat, Monkey Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E. great clips telegraph rd 63129