WebExamples of intrinsic factor in a sentence, how to use it. 15 examples: A lack of intrinsic factor may arise from an autoimmune condition targeting the… Web1) • [medisch] wezenlijk, innerlijk. (2) wezenlijk (3) van binnen afkomstig (4) intrinsiek bijv.naamw. Uitspraak: [ɪntrɪn`sik] 1) ...

Vitamin deficiency anemia - Symptoms and causes - Mayo Clinic

Intrinsic factor (IF), cobalamin binding intrinsic factor, also known as gastric intrinsic factor (GIF), is a glycoprotein produced by the parietal cells (in humans) or chief cells (in rodents) of the stomach. It is necessary for the absorption of vitamin B12 later on in the distal ileum of the small intestine. In humans, the … See more The intrinsic factor is secreted by the stomach, and so is present in the gastric juice as well as in the gastric mucous membrane. The optimum pH for its action is approximately 7. Its concentration does not correlate with … See more In pernicious anemia, which is usually an autoimmune disease, autoantibodies directed against intrinsic factor or parietal cells themselves lead to an intrinsic factor deficiency, malabsorption of vitamin B12, and subsequent megaloblastic anemia. Atrophic gastritis can … See more • Devalia V, Hamilton MS, Molloy AM (Aug 2014). "Guidelines for the diagnosis and treatment of cobalamin and folate disorders". (review). British Journal of Haematology. 166 … See more • Intrinsic+factor at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • MedlinePlus Encyclopedia: 002381 • Overview of all the structural information available in the PDB for UniProt: P27352 (Cobalamin binding intrinsic factor) at the See more WebIntrinsic factor is produced by the gastric parietal cell. Its secretion is stimulated via all pathways known to stimulate gastric acid secretion: histamine, gastrin, and acetylcholine. There is, however, a different mode of secretion for both substances: atropine, vagotomy, and H2 receptor antagoni … charly lair

Intrinsic Factor - The Definitive Guide Biology Dictionary

Web內在因子（英語： intrinsic factor, IF ）——又稱胃內在因子（ gastric intrinsic factor, GIF ）——是由胃的壁細胞分泌的一種醣蛋白，能與維生素B 12 結合成一種錯合物，這種錯合物對蛋白質水解酶有很強的抵抗力，可防止維生素B 12 被分解破壞。 當錯合物移動至迴腸時，可和迴腸黏膜上的特殊受體結合 ... WebNov 9, 2024 · Intrinsic factor blocking antibody (type 1), which blocks the binding site of vitamin B12 to intrinsic factor. This is more specific for pernicious anemia and is the … Webintrinsic factor, a glycoprotein (i.e., a complex compound containing both polysaccharide and protein components) with which vitamin B12 (cyanocobalamin) must combine to be … charly lambert