WebHOPX is an atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. HOPX acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and … Web21 mrt. 2024 · HOPX (HOP Homeobox) is a Protein Coding gene. Diseases associated with HOPX include Choriocarcinoma and Mesenteric Vascular Occlusion . UniProtKB/Swiss-Prot Summary for HOPX Gene Atypical …
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To investigate the potential role of HOPX in adult lung injury/repair, we first investigated the changes of HOPX expression in primary mouse (pm) ATII cells (95+/−3% of proSP-C expression) from wildtype mice during 2D-culture in vitro. This in vitro culture system is well-established to study trans … Meer weergeven To investigate whether HOPX is involved in the proliferation of lung epithelial cells, we silenced Hopx by siRNA in the murine alveolar epithelial cell line MLE12, which endogenously expresses HOPX. We found that … Meer weergeven Thus far, we have shown that HOPX contributes to adult lung injury/repair process in mouse lungs. Next, we sought to clarify … Meer weergeven Web1 nov. 2015 · In the adult brain, Hopx is expressed in the cerebellum (Fig. 1 A) in both Purkinje cells and Bergmann glial cells (Fig. 1 B).In the hippocampus, Hopx is found in mature astrocytes, but not in mature oligodendrocytes or neurons (Fig. 1 C–E).We note that Hopx + astrocytes are primarily located in the CA regions, but rare Hopx + astrocytes … ppt print with notes
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Web2 nov. 2024 · Homeodomain only protein (Hopx) is a regulator of cell differentiation and function, and it has also emerged as a crucial marker of specific developmental and … WebOur HOPX polyclonal antibodies are developed in Rabbit and Mouse. These antibodies have been verified by Relative expression to confirm specificity to HOPX. Find the HOPX antibody that fits your needs. Choose from 1 of 10 HOPX antibodies, which have been validated in experiments with 2 publications and 27 images featured in our data gallery. Web13 apr. 2015 · Hopx marks bipotent embryonic alveolar progenitors a-d, Sections of E15.5 lungs showing Hopx expression ( Hopx3XFlag/+ unless otherwise noted). a, Hopx is expressed in distal epithelial cells and the stalk of developing alveolar buds. The top panel is stained with a Hopx antibody. b, A subset of Hopx + cells coexpress Sox9. ppt profile template free