The biosynthesis of flavones proceeds from the phenylpropanoid pathway, which uses L-phenylalanine as a starting point. Phenylalanine ammonia lyase facilitates the deamination of L-phenylalanine to (E)-cinnamate, which is then oxidized by cinnamate 4-hydroxylase to yield p-Coumaric acid. Coenzyme A is attached to the carboxylate facilitated by 4-Coumarate-CoA ligase, forming (Coumaroyl-CoA). A chalcone …
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