WebThe purpose of the study was to compare the clinical efficacy of once-daily versus multiple dose regimens of metronidazole in inpatients with serious/systemic Bacteroides fragilis … Web(dose-adjustment assessment) Hypersensitivity, GI effects, drug interactions, QT prolongation with risk factors Metronidazole Nausea, diarrhea, disulfiram-like reactions with alcohol, metallic taste, reversible neutropenia Consider baseline LFTs GI effects. Avoid alcohol Penicillin class Tetracycline class (doxycycline, minocycline)
Diagnosis and Management of Osteomyelitis AAFP
WebOsteomyelitis is usually clinically diagnosed with support from imaging and laboratory findings. ... Metronidazole (Flagyl), 500 mg IV every 6 hours: ... 15 to 20 mg per kg per … Web• Renal dose adjustment may be ... + Metronidazole 500 mg PO/IV q8h + Vancomycin* IV (see nomogram, AUC goal 400-600), if risk for MRSA OR Amoxicillin-clavulanate 875 mg PO BID ... • Osteomyelitis would require 6-8 weeks of therapy- … how modern countries got their borders
Antimicrobial Fundamental Concepts - University of California, …
WebAbstract. Seven patients with Bacteroides fragilis infections were treated with intravenous and/or oral metronidazole. Infections treated included endocarditis, osteomyelitis, lung abscess, empyema, peritonitis, septicemia, and pelvic infection. Some patients had failed to respond to therapy with chloramphenicol or clindamycin or both. Webusual 50 mg/kg (2 g) IV daily; severe (including meningitis and brain abscess) 100 mg/kg (2 g) IV daily or 50 mg/kg (1 g) IV 12H Where possible, ceftriaxone should be avoided in neonates < 41 weeks gestation, particularly if jaundiced or receiving calcium containing solutions, including TPN 5. Pneumococci with reduced susceptibility to penicillin WebDec 11, 2024 · Bone: osteomyelitis, especially polymicrobial, associated with decubitus ulcer and other local (e.g., fecal) contamination. TREATMENT Antimicrobial agents Recommendations assume polymicrobial infection (aerobic Gram negatives and Gram positives) and empiric treatment of Bacteroides species, including B. fragilis. how modern auth works