Ezetimibe trial summary
TīmeklisThe CLEAR Tranquility trial have Investigated the safety and efficacy of bempedoic acid 180 mg once daily in addition to ezetimibe 10 mg daily in addition to stable lipid-lowering therapy in patients with a history of intolerance to at least one statin and with LDL-C levels equal to or greater than 100 mg/dL, requiring further reduction of LDL ... Tīmeklis2024. gada 29. jūl. · Baigent C, Landray MJ, Reith C, Emberson J, Wheeler DC, Tomson C, et al.; SHARP Investigators. The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial. Lancet. 2011 …
Ezetimibe trial summary
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TīmeklisClinical trial evidence suggests that bempedoic acid with ezetimibe may help lower LDL-C levels when other lipid-lowering therapies have not reduced them enough. In studies 1002-048 (CLEAR Tranquility)[3] and 1002-046 (CLEAR Serenity)[4] bempedoic Tīmeklis2024. gada 4. maijs · Objective To determine the harms of ezetimibe in people who …
TīmeklisTABLE 1 Pharmacokinetic summary: multiple 1-h i.v. ISIS 104838 infusions (mean S.D.) - "Phase I Trial of ISIS 104838, a 2′-Methoxyethyl Modified Antisense Oligonucleotide Targeting Tumor Necrosis Factor-α" TīmeklisNEJM, April 6 2024 The authors performed a prospective, randomized, open-label, adaptive, international trial involving patients with stroke due to occlusion…
TīmeklisMethods: This was a post-hoc analysis of a subset of patients who underwent PCI in the RACING trial. At 26 centres in South Korea, patients with atherosclerotic cardiovascular disease (ASCVD) were randomly assigned to receive either moderate-intensity statin with ezetimibe combination therapy (rosuvastatin 10 mg with ezetimibe 10 mg) or … TīmeklisIn summary, evolocumab is a powerful lipid-lowering drug, with an apparently large dose-dependent therapeutic range associated with a low rate of usually mild adverse events. Its efficacy seems to be evident both when administered alone and when given in association with statins and/or ezetimibe.
TīmeklisEzetimibe for treating primary heterozygous-familial and non-familial …
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