WebMar 20, 2024 · The reality of cisplatin-induced acute kidney injury (CIA) and its effects on long-term renal function remain unclear. The aim of this study was to investigate the … WebApr 9, 2024 · The most common reason for cisplatin-ineligibility is renal function impairment. Up to 40% of patients with bladder cancer have renal impairment, defined …
Cisplatin chemotherapy and renal function - PubMed
WebIt covalently binds to DNA and disrupts DNA function. 6. After cisplatin enters the cells, the chloride ligands are replaced by water molecules. 7,8. ... is a major concern when prescribing cisplatin. Renal dysfunction due to cisplatin may manifest as renal insufficiency, hypokalemia and hypomagnesemia. ... WebFeb 16, 2024 · This drug can cause severe renal toxicity, including acute renal failure. Severe renal toxicities are dose-related and cumulative. Ensure adequate hydration and … st margaret\\u0027s rc primary school galashiels
Advanced Bladder Cancer and Impaired Renal Function - Medscape
WebRenal function of cancer patients "fit" for Cisplatin chemotherapy: physician perspective Authors J Montoya 1 , H G Luna 2 , J R Amparo 2 , C Casasola 3 , G Cristal-Luna 2 Affiliations 1 Joey Montoya, MD, National … WebFor cisplatin Monitoring of patient parameters Monitor full blood count. Monitor audiology. Monitor plasma electrolytes. Nephrotoxicity Monitoring of renal function is essential. … WebNational Center for Biotechnology Information st margaret\u0027s academy ofsted